BIOCAMPUS COURSE: PROTEIN MODELING AND RATIONAL DRUG DESIGN

GVK Biosciences Private Limited Plot No: 79, Nacharam, IDA Mallapur, Landmark: Near Mallapur Manikchand Circle Hyderabad - 500076, Andhra Pradesh, INDIA BIOCAMPUS COURSE: PROTEIN MODELING AND RATIONAL DRUG DESIGN

The Human Genome Project has revealed the existence of approximately 40,000 genes, some of which could be used as new targets for drug design purposes. There is a tremendous potential in the study of their functional genomics and the corresponding protein structure vis-à-vis drug design. Almost all the leading pharmaceutical and biotech companies are focusing their efforts to discover new targets and to design new and better drugs.The aim of this course is to impart training in the basic principles of protein structure, to generate the three dimensional structure of a protein from its amino acid sequence and its utilization in the structure based drug design studies. The course covers computational approaches to the drug discovery & design processes such as analogue based designs and Pharmacophore based studies that are very useful in the absence of 3D-structural information of relevant targets. Protein Modeling & Rational Drug Design course involves the study of discovery strategies and methodologies to design a lead molecule using In-Silico methods without the available experimental approaches. Computational approaches to the drug discovery & design processes such as analogue based designs and pharmacophore based studies are covered in this module. There is a huge shortage in manpower with the requisite skill sets to perform such studies. This course tries to address such a need by imparting a comprehensive training in Protein Modeling and Rational Drug Discovery techniques. Aim The course aims at providing the participants with basic modern structural bioinformatics and homology-based protein modeling, understanding of computational modeling in the area of drug discovery. After finishing the course the participants will have: Basic understanding of ligand-protein interactions. Use Internet-based structural bioinformatics tools to analyse three-dimensional structures of a proteins and a protein-ligand complexes and perform homology-based modeling. Understand the general principles behind protein crystallization and X-Ray crystallography assess the requirements and take active part in the planning and the subsequent development of this type of projects. Be familiar with a range of ligand and structure based computational methods. Perform simple computational modeling tasks using state of the art software. Hands-on training in the use of industry-standard tools with complete suite of software & programs. Duration: 4 Months (3 hours per day, 5 days a week) Methodology: Instructor Led Training (ILT) Man to Machine Ratio: 1:1 Certification Partner: On the successful completions of the training & project, the below certificates are awarded: Accelrys Level-II bioCampus Course Contents Introduction to Rational Drug Design and Macromolecules Sequence and Structure Databases Sequence Alignment tools Molecular Modeling Homology Modeling Structure based Drug Design Analogue based Drug Design Drug Design based on Pharmacophore Analysis Programming and Algorithms in C Project Work Recruitment Opportunity Students registered with bioCampus are eligible for GVK BIO recruitments. Who can do this course? Ph. Ds in any science discipline. Postgraduates with specialization in any of the areas of molecular biology, genetics, microbiology, structural biology, chemistry, veterinary sciences, food sciences, agricultural sciences and biotechnology. B. Pharm, M. Pharm, MBBS, MD, BE/B. Tech, ME/M.Tech etc. Final Year M. Sc & BE/B. Tech, ME/M.Tech as part of their project work Students looking for Research opportunities abroad. Research Scholars in any areas of life & chemical sciences. Bachelors in Biotechnology, Microbiology, Bioinformatics, Life sciences, Biochemistry, Zoology, Botany and related discipline