II B.Pharmacy I Semester Regular Examination,November 2008.STATISTICAL METHOD AND COMPUTER APPLICATION
(a) The number of business has the sales of which are Rs 40,000.
(b) The percentage of business the sale of which are likely to range between Rs 30,000 and Rs 40,000.
2. Find carl pearson's coefficient of correlation in the following series relating to prices and supply of a commodity:
| Price(Rs) | 8 | 10 | 15 | 17 | 20 | 22 | 24 | 25 |
| Supply | 25 | 30 | 32 | 35 | 37 | 40 | 42 | 45 |
3. From the data given below find out whether the means of three samples differ significantly or not.
| Sample 1 | Sample 2 | Sample 3 |
| 20 | 19 | 13 |
| 10 | 13 | 12 |
| 17 | 17 | 10 |
| 17 | 12 | 15 |
| 16 | 9 | 5 |
4. (a) Expalin about randomized complete block design (RBD)
(b) Three varieties A,B and C of mungbean are tested in a randomized block design with four replications.The plot yield in pounds are as follows.
| A | 6 | C | 5 | A | 8 | B | 9 |
| C | 8 | A | 4 | B | 6 | C | 9 |
| B | 7 | B | 6 | C | 10 | A | 6 |
analyse the experimental yoeld and state your conclusion.
5. (a) Define a computer
(b) Explain uses and characteristics of computer.
6. Compare and contrast packages an Application program.
7. (a)Define Arrays and its type.
(b)Write a C program to find the matrix multiplication of a 3*3 matrix.
8.(a) Define the terms Bio-Technology and Bio-Engineering.
(b) Explain the role of computers in Pharmaceutical applications.
II B.Pharmacy I Semester Regular Examination,November 2008.HEALTH EDUCATION AND PATHOPHYSIOLOGY
(b) Describe the sources of vitamins and their deficiency disorders.
2. Write briefly about
(a) Significance of Family planning.
(b) Permanent methods of Family planning.
(c) Temporary methods of Family planning.
3. Write the causative agents,modes of transmission and prevention of
(a) Typhoid.
(b) Malaria.
(c) Filariasis.
(d) Rabies.
4.(a) Write about Cardiopulmonary resuscitation.
(b) Deacribe the first aid given in shock & snakebites.
5. Write about :
(a) Fertilization
(b) Sex differentiation
(c) Ogenesis.
6. (a) Discuss and differentiate necrosis and Apoptosis.
(b) Explain about atrophy as a cellular adaptation.
7. (a) Write about the vascular events incase of acute inflammation.
(b) Briefly outline the process of Repair.
8. Write the Pathophysiology of
(a) Peptic ulcer.
(b) Hypertension.
II B.Pharmacy I Semester Regular Examination,November 2008.PHYSICAL PHARMACY-II
2. Write on the following :
(a) Determination of stability constnat for complexes by distribution method and solubility method.
(b) Self-association of drugs.
3. Explain first-order reaction citing a suitable example.Derive the equation to calculate the first-order rate constnat.Describe first-order kinetics with the help of a curve.
4.(a) State and exlain "surface tension" and "interfacial tension" at the liquid interface.
(b) What is surface free energy? Explain how it is related to surface tension.
5. (a) Discuss in detail about the pharmaceutical applications on micromeritics
(b) Write a short note on different parameters used to express particle size.
6.(a) Explain the plastic and pseudo plastic behaviour of the materials with the help of flow curves and specific examples?
(b) Differentiate between Newtonian and Non Newtonian systems with suitable exaples?
7.(a) Classify the collodial systems according to states of matter ?
(b) Define Schuiz Hardy rule ? What are its applications ?
8.(a) Define emulgents.What are the desirable properties of an emulsifying agents ?
(b) Discuss the importance and mention the factors affecting the emulsion viscosity.
II B.Pharmacy I Semester Regular Examination,November 2008.PHARMACEUTICAL ORGANIC CHEMISTRY-II
(a) Pyrrole is treated with H2,Ni, at 250 degree centigardes.
(b) Discuss the structure & Nomenclature of Pyrrole.
2. Explain the following : 4-bromo-1-Methyl Imidazole treated with n-BuLi/-78 degree centigardes than DMF give C5H6N2O Carrying out the same sequence but allowing the solution to warm to 0 degree centigardes before addition of DMF gave an isomeric product.
3. What are conformational isomers/Illustrate your answer using ethane & cyclohexane as example?
4. (a)Discuss the objectives advanced aganist open chain formula of glucose
(b)How does the ring structure in general overcome the objections
(c)Deduce the nature of the ring.
5. (a) Define and classify amino acids with suitable examples.
(b) How do proteins undergo denaturation? Add a note on Pharmaceutical importance of amino acids .
6. (a) List out the important cardiac glycosides with structures and add a note on the properties and actions of glycone and aglycone parts respectively.
(b)How do you distinguish oils and fats.Define saponification vcalue,acid value and iodine values and their significance.
7. (a) Write the structure for four purine derivatives,and mention their major therapeutic applications
(b) Give a detailed account on the structures of DNA & RNA.
8.Write the mechanism and synthetic applications for the following
(a) Michael addition reaction
(b) Mannich reaction.
II B.Pharmacy I Semester Regular Examination,November 2008.PHARMACEUTICAL UNIT OPERATION-I
2. Describe the construction,working,specifications,advantages and limitations of following valves
(a) Globe valves
(b) Diaphram valves
3. Discuss briefly about working and applications of the following pumps.
(a) Gear pumps.
(b) Peristalitic pumps.
4. (a) Describe the construction and working of sintered glass filters.
(b) Compare plate and frame filter press with rotary centrifuge filters.
5.Define the following terms :
(a) Amorphous Solids.
(b) Ploymorphs.
(c) Meta Stable Polymorphs.
6. Write short notes on following :
(a) Applications of Air-conditioning.
(b) Approaches for achieving Air-Conditioning.
7. Write the following:
(a) Deascribe fluid corrosion.
(b) Explian about specific site corrosion.
8. Give a brief account on hazards in Pharmaceutical industry and the preventive safety measures.
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