JNTU HYDERABAD III. B. PHARMACY II SEMESTER REGULAR EXAMINATIONS MAY 2010 CHEMISTRY OF NATURAL DRUGS
1.(a) How will you differentiate the following by hydrolysis, explain with
chemical reaction and structure.
i) Atropine
ii) Hyoscyamine
iii) Hyosine
(b) Differentiate tropine and pseudotropine.
2. Classify ergot alkaloids and give structures, hydrolytic products and therapeutic uses of any four ergot alkaloids?
3. Explain the following.
a. Isoprene rule
b.Gem-dialkyl rule
c.Ozonolysis of terpenes
d.Stereochemistry of citral
4. Convert the following
a. Cavone to cavacrol
b. Menthol to thymol
c. Borneol to camphor
d. Camphor to borneol
5. Write on the following
a. Numbering of Bile acids, cholesterol, estrone, diels hydrocarbon
b. Synthesis of progesterone from diosgenin and cholesterol
6. Write detailed note on cardiac glycosides and mention MOA, toxicity and
thearapeutic uses?
7. Classify steroidal hormones and give brief note on the following
a. Contraceptive agents
b. Inter-conversion of estrogens
8. Write an account on
a) Insulin b) Cortisone c) Glucagon d) Thyroxine
chemical reaction and structure.
i) Atropine
ii) Hyoscyamine
iii) Hyosine
(b) Differentiate tropine and pseudotropine.
2. Classify ergot alkaloids and give structures, hydrolytic products and therapeutic uses of any four ergot alkaloids?
3. Explain the following.
a. Isoprene rule
b.Gem-dialkyl rule
c.Ozonolysis of terpenes
d.Stereochemistry of citral
4. Convert the following
a. Cavone to cavacrol
b. Menthol to thymol
c. Borneol to camphor
d. Camphor to borneol
5. Write on the following
a. Numbering of Bile acids, cholesterol, estrone, diels hydrocarbon
b. Synthesis of progesterone from diosgenin and cholesterol
6. Write detailed note on cardiac glycosides and mention MOA, toxicity and
thearapeutic uses?
7. Classify steroidal hormones and give brief note on the following
a. Contraceptive agents
b. Inter-conversion of estrogens
8. Write an account on
a) Insulin b) Cortisone c) Glucagon d) Thyroxine
JNTU HYDERABAD III. B. PHARMACY II SEMESTER REGULAR EXAMINATIONS MAY 2010 PHARMACOLOGY-II
1.a) Classify antihypertensives with suitable examples and discuss the mechanism of action and therapeutic uses of vasodilators.
b) Write a short note on plasma volume expanders.
2. Classify drugs used in angina. Discuss the pharmacology of calcium channel blockers.
3. What are arrhythmias? Discuss the pharmacology of Class I antiarrhythmic drugs.
4. a) Discuss in detail about oral anticoagulants.
b) Write in detail about Iron.
5. Classify diuretics. Write the detailed pharmacology of Frusemide.
6. a) Classify antihistaminics with suitable examples. Discuss their therapeutic uses and adverse effects.
b) Write a short note on 5HT receptors, their agonists and antagonists.
7. a) Write in detail about physiological role of Angiotensin and add a note on angiotensin antagonists.
b) Discuss the synthesis, metabolism and physiological role of Bradykinin.
8. a) Classify antiasthmatic agents with suitable examples. Discuss the pharmacology of bronchodilators.
b) Write a short note on antitussives.
b) Write a short note on plasma volume expanders.
2. Classify drugs used in angina. Discuss the pharmacology of calcium channel blockers.
3. What are arrhythmias? Discuss the pharmacology of Class I antiarrhythmic drugs.
4. a) Discuss in detail about oral anticoagulants.
b) Write in detail about Iron.
5. Classify diuretics. Write the detailed pharmacology of Frusemide.
6. a) Classify antihistaminics with suitable examples. Discuss their therapeutic uses and adverse effects.
b) Write a short note on 5HT receptors, their agonists and antagonists.
7. a) Write in detail about physiological role of Angiotensin and add a note on angiotensin antagonists.
b) Discuss the synthesis, metabolism and physiological role of Bradykinin.
8. a) Classify antiasthmatic agents with suitable examples. Discuss the pharmacology of bronchodilators.
b) Write a short note on antitussives.
JNTU HYDERABAD III.B.PHARMACY II SEMESTER REGULAR EXAMINATIONS MAY 2010 PHARMACEUTICAL JURISPRUDENCE
2. Give an account on the construction, functions and powers Council of India and State Pharmacy Council.
3. a) Explain the qualifications, duties and Procedures of inspection by Drug Inspector
b) Write the constitution of Drug Consultative Committee
4. a) Define Narcotic and Psychotropic substance. Explain the powers of central government to permit, control and regulate Narcotic and Psychotropic substances as per the act.
b) Write a note on Illicit traffic?
5. Discuss in detail about
a) Manufacture of preparations outside the bond
b) Warehousing of Alcoholic preparations
6. Write a note on
a) Drug Price Control Order
b) Factories Act 1948
7. a) Define License. Explain different types of licenses.
b) Discuss the manufacturing of drugs specified in schedule C, C1 and X
8. a) Discuss about prohibited advertisements and related offences and
penalties
b) Write a note on Indian Patents Act 1970
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